Transcriptomic and metabolomic analysis of the effects of Zhenwu decoction on kidney yang deficiency pattern in chronic kidney disease

Transcriptomic and metabolomic analysis of the effects of Zhenwu decoction on kidney yang deficiency pattern in chronic kidney disease

Objective: To explore the kidney yang deficiency pattern (KYDP) in a chronic kidney disease (CKD) rat model and the mechanisms underlying the effects of Zhenwu decoction (ZWD) by conducting transcriptomic and metabolomic analyses. Methods: Adriamycin (ADR) combined with hydrocortisone (HC) was used...

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Bibliographic Details
Main Authors:	Pengfei Zheng, Yunhua Liu, Xinjiang Zhang, Tingting Jiao, Yingjie Wu, Mengmeng Zhang, Xinxue Zhang, Zongjiang Zhao
Format:	Article
Language:	English
Published:	Elsevier 2023-04-01
Series:	Journal of Traditional Chinese Medical Sciences
Subjects:	Chronic kidney disease Kidney yang deficiency pattern Zhenwu decoction Transcriptomics Metabolomics
Online Access:	http://www.sciencedirect.com/science/article/pii/S2095754823000017

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