On the mechanisms of lysis triggered by perturbations of bacterial cell wall biosynthesis

Abstract Inhibition of bacterial cell wall synthesis by antibiotics such as β-lactams is thought to cause explosive lysis through loss of cell wall integrity. However, recent studies on a wide range of bacteria have suggested that these antibiotics also perturb central carbon metabolism, contributin...

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Bibliographic Details
Main Authors: Yoshikazu Kawai, Maki Kawai, Eilidh Sohini Mackenzie, Yousef Dashti, Bernhard Kepplinger, Kevin John Waldron, Jeff Errington
Format: Article
Language:English
Published: Nature Portfolio 2023-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-39723-8