Biological function identification of phage holin Hol-4086 and treatment of Staphylococcus aureus infection

Biological function identification of phage holin Hol-4086 and treatment of Staphylococcus aureus infection

The treatment of infections caused by drug-resistant Staphylococcus aureus has become increasingly difficult. In this study, the complete genome of phage 4086-1 against S. aureus was sequenced and shown to be 17,960 bp in size, with a GC content of 29.14%. Phylogenetic analysis demonstrated that pha...

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Bibliographic Details
Main Authors: Chenyu Zheng, Yaxin Di, Yingchun Wang, Huyang Zhao, Ruichong Wang, Guiwei Li, Xiaona Wang, Zhifu San, Yanping Jiang, Wen Cui, Jiaxuan Li, Li Wang, Xinyuan Qiao
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-02-01
Series:Frontiers in Microbiology
Subjects:
Staphylococcus aureus
phage
holin
phage perforin
phage therapy
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2025.1499566/full

Internet

https://www.frontiersin.org/articles/10.3389/fmicb.2025.1499566/full

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