Biomimetic hydrogels with mesoscale collagen architecture for patient-derived tumor organoids culture

Biomimetic hydrogels with mesoscale collagen architecture for patient-derived tumor organoids culture

Patient-derived tumor organoids (PDTOs) shows great potential as a preclinical model. However, the current methods for establishing PDTOs primarily focus on modulating local properties, such as sub-micrometer topographies. Nevertheless, they neglect to capture the global millimeter or intermediate m...

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Bibliographic Details
Main Authors: Jiaxin Wang, Zhilin Sui, Wei Huang, Zhentao Yu, Ling Guo
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2024-08-01
Series:Bioactive Materials
Subjects:
Extracellular matrix (ECM)
Mesoscale architecture
Collagen bundles
Lung cancer organoids (LCOs)
Biomimetic hydrogel
Online Access:http://www.sciencedirect.com/science/article/pii/S2452199X2400166X

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http://www.sciencedirect.com/science/article/pii/S2452199X2400166X

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