Insulin and Leptin Signaling Interact in the Mouse Kiss1 Neuron during the Peripubertal Period.

Insulin and Leptin Signaling Interact in the Mouse Kiss1 Neuron during the Peripubertal Period.

Reproduction requires adequate energy stores for parents and offspring to survive. Kiss1 neurons, which are essential for fertility, have the potential to serve as the central sensors of metabolic factors that signal to the reproductive axis the presence of stored calories. Paradoxically, obesity is...

Full description

Bibliographic Details
Main Authors: Xiaoliang Qiu, Hoangha Dao, Mengjie Wang, Amelia Heston, Kaitlyn M Garcia, Alisha Sangal, Abigail R Dowling, Latrice D Faulkner, Scott C Molitor, Carol F Elias, Jennifer W Hill
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4422586?pdf=render

Internet

http://europepmc.org/articles/PMC4422586?pdf=render

Similar Items