Tumor-Secreted Exosomal miR-222 Promotes Tumor Progression via Regulating P27 Expression and Re-Localization in Pancreatic Cancer

Tumor-Secreted Exosomal miR-222 Promotes Tumor Progression via Regulating P27 Expression and Re-Localization in Pancreatic Cancer

Background/Aims: MicroRNAs (miRNAs) or exosomes have recently been shown to play vital regulatory or communication roles in cancer biology. However, the roles and mechanisms of exosomal miRNAs in pancreatic ductal adenocarcinoma (PDAC) remain unknown. We aimed to investigate the detailed roles and m...

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Bibliographic Details
Main Authors: Zhonghu Li, Yang Tao, Xiaoya Wang, Peng Jiang, Jie Li, Minjie Peng, Xi Zhang, Kai Chen, Hui Liu, Ping Zhen, Jin Zhu, Xiangde Liu, Xiangde  Liu
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2018-11-01
Series:Cellular Physiology and Biochemistry
Subjects:
Pancreatic cancer
Exosome
miRNA
P27
Tumor invasion
Tumor prognosis
Online Access:https://www.karger.com/Article/FullText/495281

Internet

https://www.karger.com/Article/FullText/495281

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