Gene Mutations of the Three Ectodysplasin Pathway Key Players (<i>EDA</i>, <i>EDAR</i>, and <i>EDARADD</i>) Account for More than 60% of Egyptian Ectodermal Dysplasia: A Report of Seven Novel Mutations

Gene Mutations of the Three Ectodysplasin Pathway Key Players (<i>EDA</i>, <i>EDAR</i>, and <i>EDARADD</i>) Account for More than 60% of Egyptian Ectodermal Dysplasia: A Report of Seven Novel Mutations

Ectodermal dysplasia (ED) is a diverse group of genetic disorders caused by congenital defects of two or more ectodermal-derived body structures, namely, hair, teeth, nails, and some glands, e.g., sweat glands. Molecular pathogenesis of ED involves mutations of genes encoding key proteins of major d...

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Bibliographic Details
Main Authors: Hoda A. Ahmed, Ghada Y. El-Kamah, Eman Rabie, Mostafa I. Mostafa, Maha R. Abouzaid, Nehal F. Hassib, Mennat I. Mehrez, Mohamed A. Abdel-Kader, Yasmine H. Mohsen, Suher K. Zada, Khalda S. Amr, Inas S. M. Sayed
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Genes
Subjects:
ectodysplasin A
ectodermal eysplasia
<i>EDA</i>
<i>EDAR</i>
<i>EDARADD</i>
<i>WNT10A</i>
Online Access:https://www.mdpi.com/2073-4425/12/9/1389

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https://www.mdpi.com/2073-4425/12/9/1389

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