Biochemical Fractionation of Human α-Synuclein in a <i>Drosophila</i> Model of Synucleinopathies

Synucleinopathies are a group of central nervous system pathologies that are characterized by the intracellular accumulation of misfolded and aggregated α-synuclein in proteinaceous depositions known as Lewy Bodies (LBs). The transition of α-synuclein from its physiological to pathological form has...

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Bibliographic Details
Main Authors: Khondamir Imomnazarov, Joshua Lopez-Scarim, Ila Bagheri, Valerie Joers, Malú Gámez Tansey, Alfonso Martín-Peña
Format: Article
Language:English
Published: MDPI AG 2024-03-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/25/7/3643