Biophysical analysis of the interaction of the serum protein human β2GPI with bacterial lipopolysaccharide

Biophysical analysis of the interaction of the serum protein human β2GPI with bacterial lipopolysaccharide

There are several human serum proteins for which no clear role is yet known. Among these is the abundant serum protein beta2-glycoprotein-I (β2GPI), which is known to bind to negatively charged phospholipids as well as to bacterial lipopolysaccharides (LPS), and was therefore proposed to play a role...

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Bibliographic Details
Main Authors: Anna Gries, Ruth Prassl, Satoshi Fukuoka, Manfred Rössle, Yani Kaconis, Lena Heinbockel, Thomas Gutsmann, Klaus Brandenburg
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:FEBS Open Bio
Subjects:
Human glycoprotein β2GPI
Lipopolysaccharide
Cytokine production
Immune modulation
LAL test
Online Access:http://www.sciencedirect.com/science/article/pii/S2211546314000448

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http://www.sciencedirect.com/science/article/pii/S2211546314000448

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