Insulin-like 3 affects zebrafish spermatogenic cells directly and via Sertoli cells

Insulin-like 3 (Insl3) belongs to a class of peptide hormones that are expressed in the Leydig cells and, in zebrafish, under the control of folliclestimulating hormone (Fsh) in the pituitary. Using insl3 knockout zebrafish, the authors found that Insl3 regulates spermatogonia differentiation and ap...

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Bibliographic Details
Main Authors: Diego Crespo, Luiz H. C. Assis, Yu Ting Zhang, Diego Safian, Tomasz Furmanek, Kai Ove Skaftnesmo, Birgitta Norberg, Wei Ge, Yung-Ching Choi, Marjo J. den Broeder, Juliette Legler, Jan Bogerd, Rüdiger W. Schulz
Format: Article
Language:English
Published: Nature Portfolio 2021-02-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-021-01708-y