Identification of a Maturation Plasma Cell Index through a Highly Sensitive Droplet Digital PCR Assay Gene Expression Signature Validation in Newly Diagnosed Multiple Myeloma Patients

Identification of a Maturation Plasma Cell Index through a Highly Sensitive Droplet Digital PCR Assay Gene Expression Signature Validation in Newly Diagnosed Multiple Myeloma Patients

DNA microarrays and RNA-based sequencing approaches are considered important discovery tools in clinical medicine. However, cross-platform reproducibility studies undertaken so far have highlighted that microarrays are not able to accurately measure gene expression, particularly when they are expres...

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Bibliographic Details
Main Authors: Marina Martello, Vincenza Solli, Rosalinda Termini, Ajsi Kanapari, Daniel Remondini, Enrica Borsi, Andrea Poletti, Silvia Armuzzi, Barbara Taurisano, Ilaria Vigliotta, Gaia Mazzocchetti, Elena Zamagni, Alessandra Merlotti, Paola Tacchetti, Lucia Pantani, Serena Rocchi, Ilaria Rizzello, Katia Mancuso, Michele Cavo, Carolina Terragna
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:International Journal of Molecular Sciences
Subjects:
multiple myeloma
hedgehog signaling
self-renewal
digital PCR
plasma cell maturation
differentiation stages
Online Access:https://www.mdpi.com/1422-0067/23/20/12450

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https://www.mdpi.com/1422-0067/23/20/12450

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