Platelet-derived growth factor receptor beta is required for embryonic specification and confinement of the adult white adipose lineage

Summary: White adipose tissue (WAT) development and adult homeostasis rely on distinct adipocyte progenitor cells (APCs). While adult APCs are defined early during embryogenesis and generate adipocytes after WAT organogenesis, the mechanisms underlying adult adipose lineage determination and preserv...

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Bibliographic Details
Main Authors: Abigail M. Benvie, Derek Lee, Yuwei Jiang, Daniel C. Berry
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223027591