The Proteome and Secretome of Cortical Brain Cells Infected With Herpes Simplex Virus

The Proteome and Secretome of Cortical Brain Cells Infected With Herpes Simplex Virus

Infections of the brain with herpes simplex virus type 1 (HSV-1) cause life-threatening Herpes simplex encephalitis (HSE) characterized by viral replication in neurons and neuro-inflammation including an infiltration of peripheral immune cells. HSV-1 reprograms host cells to foster its own replicati...

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Bibliographic Details
Main Authors: Niko Hensel, Verena Raker, Benjamin Förthmann, Anna Buch, Beate Sodeik, Andreas Pich, Peter Claus
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Neurology
Subjects:
herpes simplex virus-1
encephalitis
NEK7
inflammasome
Rab GTPases
ArfGap1
Online Access:https://www.frontiersin.org/article/10.3389/fneur.2020.00844/full

Internet

https://www.frontiersin.org/article/10.3389/fneur.2020.00844/full

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