Clinical trial of insulin-like growth factor-1 in Phelan-McDermid syndrome

Clinical trial of insulin-like growth factor-1 in Phelan-McDermid syndrome

Abstract Background Phelan-McDermid syndrome (PMS) is caused by haploinsufficiency of the SHANK3 gene and is characterized by global developmental delays and autism spectrum disorder (ASD). Based on several converging lines of preclinical and clinical evidence supporting the use of insulin-like grow...

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Bibliographic Details
Main Authors: A. Kolevzon, M. S. Breen, P. M. Siper, D. Halpern, Y. Frank, H. Rieger, J. Weismann, M. P. Trelles, B. Lerman, R. Rapaport, J. D. Buxbaum
Format: Article
Language:English
Published: BMC 2022-04-01
Series:Molecular Autism
Subjects:
Phelan-McDermid syndrome
PMS
shank3
Autism spectrum disorder
ASD
Insulin-like growth factor-1
Online Access:https://doi.org/10.1186/s13229-022-00493-7

Internet

https://doi.org/10.1186/s13229-022-00493-7

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