Total Synthesis and Stereochemical Assignment of Nostosin B

Nostosins A and B were isolated from a hydrophilic extract of Nostoc sp. strain from Iran, which exhibits excellent tryps inhibitory activity. Nostosin A was the most potent natural tripeptide aldehyde as trypsin inhibitor up to now. Both R‐ and S‐2‐hydroxy‐4‐(4‐hydroxy‐phenyl) butanoic acid (Hhpba...

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Bibliographic Details
Main Authors: Xiaoji Wang, Junmin Feng, Zhengshuang Xu, Tao Ye, Yi Meng, Zhiyu Zhang
Format: Article
Language:English
Published: MDPI AG 2017-02-01
Series:Marine Drugs
Subjects:
Online Access:http://www.mdpi.com/1660-3397/15/3/58