Kidney-specific methylation patterns correlate with kidney function and are lost upon kidney disease progression

Abstract Background Chronological and biological age correlate with DNA methylation levels at specific sites in the genome. Linear combinations of multiple methylation sites, termed epigenetic clocks, can inform us the chronological age and predict multiple health-related outcomes. However, why some...

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Bibliographic Details
Main Authors: Naor Sagy, Noa Meyrom, Pazit Beckerman, Oren Pleniceanu, Daniel Z. Bar
Format: Article
Language:English
Published: BMC 2024-02-01
Series:Clinical Epigenetics
Online Access:https://doi.org/10.1186/s13148-024-01642-w