Subcellular analysis of blood-brain barrier function by micro-impalement of vessels in acute brain slices

Subcellular analysis of blood-brain barrier function by micro-impalement of vessels in acute brain slices

The blood-brain barrier (BBB) tightly and dynamically regulates exchange with the brain. Here, the authors report a brain slice approach to study the native BBB in a highly controlled manner by combining intravascular perfusion and multiphoton microscopy.

Bibliographic Details
Main Authors: Amira Sayed Hanafy, Pia Steinlein, Julika Pitsch, Mariella Hurtado Silva, Natascha Vana, Albert J. Becker, Mark Evan Graham, Susanne Schoch, Alf Lamprecht, Dirk Dietrich
Format: Article
Language:English
Published: Nature Portfolio 2023-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-36070-6

Internet

https://doi.org/10.1038/s41467-023-36070-6

Similar Items