The progression of severe aplastic anemia to hypoplastic leukemia in a long-term observation after the administration of pegylated rHuMGDF

The progression of severe aplastic anemia to hypoplastic leukemia in a long-term observation after the administration of pegylated rHuMGDF

Thrombopoietin (TPO) is a critical regulator of hematopoiesis. We previously reported that a severe aplastic anemia (SAA) who received a short-term administration of pegylated recombinant human megakaryocyte growth and development factor (rHuMGDF). A trilineage hematologic response was induced, howe...

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Bibliographic Details
Main Authors: Maho Ishikawa, Akira Matsuda, Daisuke Okamura, Tomoya Maeda, Nobutaka Kawai, Norio Asou, Masami Bessho
Format: Article
Language:English
Published: MDPI AG 2018-09-01
Series:Hematology Reports
Subjects:
Aplastic anemia
acute myeloid leukemia
thrombopoietin
clonal evolution
Online Access:https://www.pagepress.org/journals/index.php/hr/article/view/7679

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https://www.pagepress.org/journals/index.php/hr/article/view/7679

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