Antinociceptive effect of Nephelium lappaceum L. fruit peel and the participation of nitric oxide, opioid receptors, and ATP-sensitive potassium channels

Antinociceptive effect of Nephelium lappaceum L. fruit peel and the participation of nitric oxide, opioid receptors, and ATP-sensitive potassium channels

Introduction:Nephelium lappaceum L. (Sapindaceae) is a plant known as rambutan. It is used for various purposes in traditional medicine.Objective: We aimed to evaluate the antinociceptive effects of the ethanol extract of the fruit peel of N. lappaceum (EENL), the mechanisms involved in these effect...

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Main Authors: Alan Santos Oliveira, Laiza Santos Biano, David Nascimento Palmeira, Damião Rabelo de Almeida, Mônica Lopes-Ferreira, Markus Kohlhoff, Jordano Augusto Carvalho Sousa, Geraldo Célio Brandão, Ana Mara de Oliveira e Silva, Renata Grespan, Enilton Aparecido Camargo
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Pharmacology
Subjects:
Nephelium lappaceum
fruit peel
antinociception
locomotor activity
toxicity
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1287580/full

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https://www.frontiersin.org/articles/10.3389/fphar.2023.1287580/full

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