Study of exopolysaccharide produced by Streptomyces rochie strain OF1 and its effect as ameliorative on osteoarthritis in rats via inhibiting TNF-α/COX2 pathway

Study of exopolysaccharide produced by Streptomyces rochie strain OF1 and its effect as ameliorative on osteoarthritis in rats via inhibiting TNF-α/COX2 pathway

Abstract Background Carbohydrates are known as the main natural products of life activities. Results Streptomyces rochie strain OF1 isolated from a mangrove tree produced exopolysaccharide S5 (EPSS5) (14.2 gl−1) containing uronic acid 21.98% sulfate content of 11.65 mg/ml, and a viscosity of 1.35 mm...

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Bibliographic Details
Main Authors: Sahar Saleh Mohamed, Mohamed E. El Awady, Sayeda Abdelrazek Abdelhamid, Ahmed Abdelghani Hamed, Abeer A. A. Salama, Manal S. Selim
Format: Article
Language:English
Published: Elsevier 2023-02-01
Series:Journal of Genetic Engineering and Biotechnology
Subjects:
Exopolysaccharide
Streptomyces rochie
Antimicrobial
Antibiofilm
Inflammatory biomarkers
Online Access:https://doi.org/10.1186/s43141-023-00471-3

Internet

https://doi.org/10.1186/s43141-023-00471-3

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