Identification and Validation of Protein Biomarkers of Response to Neoadjuvant Platinum Chemotherapy in Muscle Invasive Urothelial Carcinoma.

Identification and Validation of Protein Biomarkers of Response to Neoadjuvant Platinum Chemotherapy in Muscle Invasive Urothelial Carcinoma.

BACKGROUND:The 5-year cancer specific survival (CSS) for patients with muscle invasive urothelial carcinoma of the bladder (MIBC) treated with cystectomy alone is approximately 50%. Platinum based neoadjuvant chemotherapy (NAC) plus cystectomy results in a marginal 5-10% increase in 5-year CSS in MI...

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Bibliographic Details
Main Authors: Alexander S Baras, Nilay Gandhi, Enrico Munari, Sheila Faraj, Luciana Shultz, Luigi Marchionni, Mark Schoenberg, Noah Hahn, Mohammad Obaidul Hoque, David Berman, Trinity J Bivalacqua, George Netto
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4521868?pdf=render

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http://europepmc.org/articles/PMC4521868?pdf=render

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