RhoB as a tumor suppressor: It’s all about localization
The small GTPase RhoB is distinguished from other Rho proteins by its unique subcellular localization in endosomes, multivesicular bodies, and nucleus. Despite high sequence homology with RhoA and RhoC, RhoB is mainly associated with tumor suppressive function, while RhoA and RhoC support oncogenic...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2023-06-01
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Series: | European Journal of Cell Biology |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0171933523000286 |