Contribution of Oxidative Stress (OS) in Calcific Aortic Valve Disease (CAVD): From Pathophysiology to Therapeutic Targets

Contribution of Oxidative Stress (OS) in Calcific Aortic Valve Disease (CAVD): From Pathophysiology to Therapeutic Targets

Calcific aortic valve disease (CAVD) is a major cause of cardiovascular mortality and morbidity, with increased prevalence and incidence. The underlying mechanisms behind CAVD are complex, and are mainly illustrated by inflammation, mechanical stress (which induces prolonged aortic valve endothelial...

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Bibliographic Details
Main Authors: Daniela Maria Tanase, Emilia Valasciuc, Evelina Maria Gosav, Mariana Floria, Claudia Florida Costea, Nicoleta Dima, Ionut Tudorancea, Minela Aida Maranduca, Ionela Lacramioara Serban
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Cells
Subjects:
oxidative stress
calcific aortic valve disease
bicuspid aortic valve
valvular interstitial cells
antioxidants
therapeutic targets
Online Access:https://www.mdpi.com/2073-4409/11/17/2663

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https://www.mdpi.com/2073-4409/11/17/2663

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