A distinct immune landscape in anti-synthetase syndrome profiled by a single-cell genomic study

A distinct immune landscape in anti-synthetase syndrome profiled by a single-cell genomic study

ObjectivesThe objective of this study was to profile the transcriptional profiles of peripheral blood mononuclear cells (PBMCs) and their immune repertoires affected by anti-synthetase syndrome (ASS) at the single-cell level.MethodsWe performed single-cell RNA sequencing (scRNA-seq) analysis of PBMC...

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Bibliographic Details
Main Authors: Jiayu Ding, Yanmei Li, Zhiqin Wang, Feng Han, Ming Chen, Jun Du, Tong Yang, Mei Zhang, Yingai Wang, Jing Xu, Gaoya Wang, Yong Xu, Xiuhua Wu, Jian Hao, Xinlei Liu, Guangxin Zhang, Na Zhang, Wenwen Sun, Zhigang Cai, Wei Wei
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-10-01
Series:Frontiers in Immunology
Subjects:
anti-synthetase syndrome (ASS)
single-cell RNA sequencing (scRNA-seq)
mucosal-associated invariant T (MAIT) cell
IFN-II
auto-immune diseases
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1436114/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2024.1436114/full

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