Expression and purification of human diacylglycerol kinase α from baculovirus-infected insect cells for structural studies
Diacylglycerol kinases (DGKs) are lipid kinases that modulate the levels of lipid second messengers, diacylglycerol and phosphatidic acid. Recently, increasing attention has been paid to its α isozyme (DGKα) as a potential target for cancer immunotherapy. DGKα consists of the N-terminal regulatory d...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
PeerJ Inc.
2018-08-01
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Series: | PeerJ |
Subjects: | |
Online Access: | https://peerj.com/articles/5449.pdf |