Network analyses of upper and lower airway transcriptomes identify shared mechanisms among children with recurrent wheezing and school-age asthma

Network analyses of upper and lower airway transcriptomes identify shared mechanisms among children with recurrent wheezing and school-age asthma

BackgroundPredicting which preschool children with recurrent wheezing (RW) will develop school-age asthma (SA) is difficult, highlighting the critical need to clarify the pathogenesis of RW and the mechanistic relationship between RW and SA. Despite shared environmental exposures and genetic determi...

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Bibliographic Details
Main Authors: Zhili Wang, Yu He, Qinyuan Li, Yan Zhao, Guangli Zhang, Zhengxiu Luo
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Immunology
Subjects:
cell deconvolution
gene co-expression network
machine learning
recurrent wheezing
school-age asthma
scRNA-seq
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1087551/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1087551/full

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