Parkinson’s disease-associated, sex-specific changes in DNA methylation at PARK7 (DJ-1), SLC17A6 (VGLUT2), PTPRN2 (IA-2β), and NR4A2 (NURR1) in cortical neurons
Abstract Evidence for epigenetic regulation playing a role in Parkinson’s disease (PD) is growing, particularly for DNA methylation. Approximately 90% of PD cases are due to a complex interaction between age, genes, and environmental factors, and epigenetic marks are thought to mediate the relations...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2022-09-01
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Series: | npj Parkinson's Disease |
Online Access: | https://doi.org/10.1038/s41531-022-00355-2 |