Parkinson’s disease-associated, sex-specific changes in DNA methylation at PARK7 (DJ-1), SLC17A6 (VGLUT2), PTPRN2 (IA-2β), and NR4A2 (NURR1) in cortical neurons

Abstract Evidence for epigenetic regulation playing a role in Parkinson’s disease (PD) is growing, particularly for DNA methylation. Approximately 90% of PD cases are due to a complex interaction between age, genes, and environmental factors, and epigenetic marks are thought to mediate the relations...

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Bibliographic Details
Main Authors: Joseph Kochmanski, Nathan C. Kuhn, Alison I. Bernstein
Format: Article
Language:English
Published: Nature Portfolio 2022-09-01
Series:npj Parkinson's Disease
Online Access:https://doi.org/10.1038/s41531-022-00355-2

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