Chemical and biological characterization of vaccine adjuvant QS-21 produced via plant cell culture

Chemical and biological characterization of vaccine adjuvant QS-21 produced via plant cell culture

Summary: Many vaccines, including those using recombinant antigen subunits, rely on adjuvant(s) to enhance the efficacy of the host immune responses. Among the few adjuvants clinically approved, QS-21, a saponin-based immunomodulatory molecule isolated from the tree bark of Quillaja saponaria (QS) i...

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Bibliographic Details
Main Authors: Xiangmin Lv, Jesse Martin, Heather Hoover, Bishnu Joshi, Margaret Wilkens, David A. Ullisch, Thomas Leibold, John S. Juchum, Sanket Revadkar, Barbara Kalinovska, Justin Keith, Adam Truby, Gui Liu, Elaine Sun, John Haserick, Jon DeGnore, Joseph Conolly, Adrian V.S. Hill, John Baldoni, Charlotte Kensil, Dan Levey, Alexandra J. Spencer, Gilbert Gorr, Mark Findeis, Antoine Tanne
Format: Article
Language:English
Published: Elsevier 2024-03-01
Series:iScience
Subjects:
natural product synthesis
medical biochemistry
cell
Phytochemistry
Bioactive plant product
Online Access:http://www.sciencedirect.com/science/article/pii/S258900422400227X

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http://www.sciencedirect.com/science/article/pii/S258900422400227X

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