Ariadne: synthetic long read deconvolution using assembly graphs

Abstract Synthetic long read sequencing techniques such as UST’s TELL-Seq and Loop Genomics’ LoopSeq combine 3 $$'$$ ′ barcoding with standard short-read sequencing to expand the range of linkage resolution from hundreds to tens of thousands of base-pairs. However, the lack of a 1:1 corresponde...

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Bibliographic Details
Main Authors: Lauren Mak, Dmitry Meleshko, David C. Danko, Waris N. Barakzai, Salil Maharjan, Natan Belchikov, Iman Hajirasouliha
Format: Article
Language:English
Published: BMC 2023-08-01
Series:Genome Biology
Subjects:
Online Access:https://doi.org/10.1186/s13059-023-03033-5