Analyzing and Modeling the Dysfunction of Inhibitory Neurons in Alzheimer's Disease.

Alzheimer's disease (AD) is characterized by the abnormal proteolytic processing of amyloid precursor protein, resulting in increased production of a self-aggregating form of beta amyloid (Aβ). Several lines of work on AD patients and transgenic mice with high Aβ levels exhibit altered rhythmic...

Full description

Bibliographic Details
Main Authors: Carlos Perez, Jokubas Ziburkus, Ghanim Ullah
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5201300?pdf=render