Analyzing and Modeling the Dysfunction of Inhibitory Neurons in Alzheimer's Disease.
Alzheimer's disease (AD) is characterized by the abnormal proteolytic processing of amyloid precursor protein, resulting in increased production of a self-aggregating form of beta amyloid (Aβ). Several lines of work on AD patients and transgenic mice with high Aβ levels exhibit altered rhythmic...
Main Authors: | Carlos Perez, Jokubas Ziburkus, Ghanim Ullah |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2016-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC5201300?pdf=render |
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