A novel telomerase-derived peptide GV1001-mediated inhibition of angiogenesis: Regulation of VEGF/VEGFR-2 signaling pathways

GV1001, a human telomerase reverse transcriptase catalytic subunit-derived 16-mer peptide, has been developed as a novel anticancer vaccine against various cancers including pancreatic cancer. In the current study, we demonstrate the regulatory roles and mechanisms of GV1001 in endothelial cell resp...

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Bibliographic Details
Main Authors: Jae Hyeon Kim, Young-Rak Cho, Eun-Kyung Ahn, Sunho Kim, Surim Han, Sung Joon Kim, Gyu-Un Bae, Joa Sub Oh, Dong-Wan Seo
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:Translational Oncology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523322002054