Use of a gene score of multiple low-modest effect size variants can predict the risk of obesity better than the individual SNPs

Abstract Background Obesity is a complex disorder, the development of which is modulated by a multitude of environmental, behavioral and genetic factors. The common forms of obesity are polygenic in nature which means that many variants in the same or different genes act synergistically and affect t...

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Bibliographic Details
Main Authors: Shabana, Saleem Ullah Shahid, Shahida Hasnain
Format: Article
Language:English
Published: BMC 2018-07-01
Series:Lipids in Health and Disease
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12944-018-0806-5