Use of a gene score of multiple low-modest effect size variants can predict the risk of obesity better than the individual SNPs
Abstract Background Obesity is a complex disorder, the development of which is modulated by a multitude of environmental, behavioral and genetic factors. The common forms of obesity are polygenic in nature which means that many variants in the same or different genes act synergistically and affect t...
Main Authors: | Shabana, Saleem Ullah Shahid, Shahida Hasnain |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2018-07-01
|
Series: | Lipids in Health and Disease |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12944-018-0806-5 |
Similar Items
-
Polygenic Risk Score Impact on Susceptibility to Age-Related Macular Degeneration in Polish Patients
by: Anna Wąsowska, et al.
Published: (2022-12-01) -
Evaluation of genetic variants related to lipid levels among the North Indian population
by: Gagandeep Kaur Walia, et al.
Published: (2024-01-01) -
Polygene Risk Scores
by: James Woodward, et al.
Published: (2023-07-01) -
Discrimination Exposure and Polygenic Risk for Obesity in Adulthood: Testing Gene-Environment Correlations and Interactions
by: Adolfo G. Cuevas, et al.
Published: (2023-02-01) -
The False Dawn of Polygenic Risk Scores for Human Disease Prediction
by: Anthony F. Herzig, et al.
Published: (2022-07-01)