Genetic analysis of polymorphisms in the kalirin gene for association with age-at-onset in European Huntington disease patients

<p>Abstract</p> <p>Background</p> <p>Huntington disease (HD) is caused by an expanded CAG repeat in the <it>HD</it> gene. Although the length of the CAG repeat strongly correlates with the age-at-onset (AAO), AAO in HD individuals may differ dramatically in...

Full description

Bibliographic Details
Main Authors: Tsai Yu-Chun, Metzger Silke, Riess Olaf, Soehn Anne S, Nguyen Huu
Format: Article
Language:English
Published: BMC 2012-06-01
Series:BMC Medical Genetics
Online Access:http://www.biomedcentral.com/1471-2350/13/48