Neuronal GHS-R Differentially Modulates Feeding Patterns under Normal and Obesogenic Conditions

Neuronal GHS-R Differentially Modulates Feeding Patterns under Normal and Obesogenic Conditions

The orexigenic hormone ghrelin increases food intake and promotes obesity through its receptor, growth hormone secretagogue receptor (GHS-R). We previously reported two neuron-specific GHS-R knockout mouse lines, namely pan-neuronal deletion by Syn1-cre and hypothalamic deletion by AgRP-cre, exhibit...

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Bibliographic Details
Main Authors: Jong Han Lee, Bingzhong Xue, Zheng Chen, Yuxiang Sun
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Biomolecules
Subjects:
ghrelin
growth hormone secretagogue receptor (GHS-R)
diet-induced obesity
feeding behaviors
meal size
meal duration
Online Access:https://www.mdpi.com/2218-273X/12/2/293

Internet

https://www.mdpi.com/2218-273X/12/2/293

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