The role of PD-1 signaling in health and immune-related diseases

The role of PD-1 signaling in health and immune-related diseases

Programmed cell death 1 receptor (PD-1) and its ligands constitute an inhibitory pathway to mediate the mechanism of immune tolerance and provide immune homeostasis. Significantly, the binding partners of PD-1 and its associated ligands are diverse, which facilitates immunosuppression in cooperation...

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Bibliographic Details
Main Authors: Ru-Yue Chen, Yun Zhu, Yun-Yan Shen, Qin-Ying Xu, Han-Yun Tang, Ning-Xun Cui, Lu Jiang, Xiao-Mei Dai, Wei-Qing Chen, Qiang Lin, Xiao-Zhong Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Immunology
Subjects:
programmed cell death 1 receptor
immune checkpoint proteins
immune tolerance
tumor microenvironment
autoimmune diseases
immunotherapy
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1163633/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2023.1163633/full

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