Metabolic guidance and stress in tumors modulate antigen-presenting cells

Abstract Successful antitumor immunity largely relies on efficient T cell priming by antigen-presenting cells (APCs); however, the capacity of APCs is found to be defective in many cancers. Metabolically reprogrammed cancer cells support the energetic and biosynthetic demands of their high prolifera...

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Bibliographic Details
Main Authors: Jaeoh Park, Limei Wang, Ping-Chih Ho
Format: Article
Language:English
Published: Nature Publishing Group 2022-10-01
Series:Oncogenesis
Online Access:https://doi.org/10.1038/s41389-022-00438-y