Metabolic guidance and stress in tumors modulate antigen-presenting cells
Abstract Successful antitumor immunity largely relies on efficient T cell priming by antigen-presenting cells (APCs); however, the capacity of APCs is found to be defective in many cancers. Metabolically reprogrammed cancer cells support the energetic and biosynthetic demands of their high prolifera...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2022-10-01
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Series: | Oncogenesis |
Online Access: | https://doi.org/10.1038/s41389-022-00438-y |