Evolution towards simplicity in bacterial small heat shock protein system

Evolution can tinker with multi-protein machines and replace them with simpler single-protein systems performing equivalent functions in an equally efficient manner. It is unclear how, on a molecular level, such simplification can arise. With ancestral reconstruction and biochemical analysis, we hav...

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Bibliographic Details
Main Authors: Piotr Karaś, Klaudia Kochanowicz, Marcin Pitek, Przemyslaw Domanski, Igor Obuchowski, Barlomiej Tomiczek, Krzysztof Liberek
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2023-12-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/89813