Remodeling of the ribosomal quality control and integrated stress response by viral ubiquitin deconjugases
Abstract The strategies adopted by viruses to reprogram the translation and protein quality control machinery and promote infection are poorly understood. Here, we report that the viral ubiquitin deconjugase (vDUB)—encoded in the large tegument protein of Epstein-Barr virus (EBV BPLF1)—regulates the...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2023-12-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-023-43946-0 |