A Polymorphism in the TMPRSS2 Gene Increases the Risk of Death in Older Patients Hospitalized with COVID-19

A Polymorphism in the TMPRSS2 Gene Increases the Risk of Death in Older Patients Hospitalized with COVID-19

Background: Transmembrane serine protease type 2 (TMPRSS2) and angiotensin-converting enzyme 2 (ACE2) are the main molecules involved in the entry of SARS-CoV-2 into host cells. Changes in TMPRSS2 expression levels caused by single nucleotide polymorphisms (SNPs) may contribute to the outcome of COV...

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Bibliographic Details
Main Authors: Clara Caldeira de Andrade, Ana Tércia Paulo Silva, Luydson Richardson Silva Vasconcelos, Pablo Rafael Silveira Oliveira, Carlos Dornels Freire de Souza, Anderson da Costa Armstrong, Rodrigo Feliciano do Carmo
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Viruses
Subjects:
coronavirus
mortality
polymorphism
SARS-CoV-2
TMPRSS2
Online Access:https://www.mdpi.com/1999-4915/14/11/2557

Internet

https://www.mdpi.com/1999-4915/14/11/2557

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