Targeted PHA Microsphere-Loaded Triple-Drug System with Sustained Drug Release for Synergistic Chemotherapy and Gene Therapy

Targeted PHA Microsphere-Loaded Triple-Drug System with Sustained Drug Release for Synergistic Chemotherapy and Gene Therapy

The combination of paclitaxel (PTX) with other chemotherapy drugs (e.g., gemcitabine, GEM) or genetic drugs (e.g., siRNA) has been shown to enhance therapeutic efficacy against tumors, reduce individual drug dosages, and prevent drug resistance associated with single-drug treatments. However, the va...

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Bibliographic Details
Main Authors: Shuo Wang, Chao Zhang, Huandi Liu, Xueyu Fan, Shuangqing Fu, Wei Li, Honglei Zhang
Format: Article
Language:English
Published: MDPI AG 2024-10-01
Series:Nanomaterials
Subjects:
amphiphilic core shell
polyhydroxyalkanoates
chemogene drugs
synergetic therapy
sustained drug release
microparticles
Online Access:https://www.mdpi.com/2079-4991/14/20/1657

Internet

https://www.mdpi.com/2079-4991/14/20/1657

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