Nasal epithelial cell culture fluorescence recovery after photobleaching predicts cystic fibrosis therapeutic response

Nasal epithelial cell culture fluorescence recovery after photobleaching predicts cystic fibrosis therapeutic response

Background Human nasal epithelial (HNE) cells can be sampled noninvasively and cultured to provide a model of the airway epithelium that reflects cystic fibrosis (CF) pathophysiology. We hypothesised that in vitro measures of HNE cell physiology would correlate directly with in vivo measures of lung...

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Bibliographic Details
Main Authors: Timothy E. Corcoran, Carol A. Bertrand, Michael M. Myerburg, Daniel J. Weiner, Sheila A. Frizzell, Anna Li, Brittani Agostini, Robert S. Parker, Monica E. Shapiro, Ashok Muthukrishnan, Nicholas D. Hages, Brian P. Mulhern, Joseph M. Pilewski
Format: Article
Language:English
Published: European Respiratory Society 2022-12-01
Series:ERJ Open Research
Online Access:http://openres.ersjournals.com/content/8/4/00382-2022.full

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http://openres.ersjournals.com/content/8/4/00382-2022.full

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