Nasal epithelial cell culture fluorescence recovery after photobleaching predicts cystic fibrosis therapeutic response
Background Human nasal epithelial (HNE) cells can be sampled noninvasively and cultured to provide a model of the airway epithelium that reflects cystic fibrosis (CF) pathophysiology. We hypothesised that in vitro measures of HNE cell physiology would correlate directly with in vivo measures of lung...
Main Authors: | Timothy E. Corcoran, Carol A. Bertrand, Michael M. Myerburg, Daniel J. Weiner, Sheila A. Frizzell, Anna Li, Brittani Agostini, Robert S. Parker, Monica E. Shapiro, Ashok Muthukrishnan, Nicholas D. Hages, Brian P. Mulhern, Joseph M. Pilewski |
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Format: | Article |
Language: | English |
Published: |
European Respiratory Society
2022-12-01
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Series: | ERJ Open Research |
Online Access: | http://openres.ersjournals.com/content/8/4/00382-2022.full |
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