Peptone‐mediated glucagon‐like peptide‐1 secretion depends on intestinal absorption and activation of basolaterally located Calcium‐Sensing Receptors

Abstract Protein intake robustly stimulates the secretion of the incretin hormone, glucagon‐like peptide‐1 (GLP‐1) but the molecular mechanisms involved are not well understood. In particular, it is unknown whether proteins stimulate secretion by activation of luminal or basolateral sensors. We char...

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Bibliographic Details
Main Authors: Ida M. Modvig, Rune E. Kuhre, Jens Juul Holst
Format: Article
Language:English
Published: Wiley 2019-04-01
Series:Physiological Reports
Subjects:
Online Access:https://doi.org/10.14814/phy2.14056