Novel protocol for multiple-dose oral administration of the L-type Ca2+ channel blocker isradipine in mice: A dose-finding pharmacokinetic study

Studies in genetically modified animals and human genetics have recently provided new insight into the role of voltage-gated L-type Ca2+ channels in human disease. Therefore, the inhibition of L-type Ca2+ channels in vivo in wildtype and mutant mice by potent dihydropyridine (DHP) Ca2+ channel block...

Повний опис

Бібліографічні деталі
Автори: Tamara Theiner, Nadine J. Ortner, Herbert Oberacher, Gospava Stojanovic, Petronel Tuluc, Jörg Striessnig
Формат: Стаття
Мова:English
Опубліковано: Taylor & Francis Group 2024-12-01
Серія:Channels
Предмети:
Онлайн доступ:https://www.tandfonline.com/doi/10.1080/19336950.2024.2335469