Empty conformers of HLA-B preferentially bind CD8 and regulate CD8+ T cell function
When complexed with antigenic peptides, human leukocyte antigen (HLA) class I (HLA-I) molecules initiate CD8+ T cell responses via interaction with the T cell receptor (TCR) and co-receptor CD8. Peptides are generally critical for the stable cell surface expression of HLA-I molecules. However, for H...
| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | English |
| Publicado em: |
eLife Sciences Publications Ltd
2018-05-01
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| Colecção: | eLife |
| Assuntos: | |
| Acesso em linha: | https://elifesciences.org/articles/36341 |