A cautionary tale of low-pass sequencing and imputation with respect to haplotype accuracy

Abstract Background Low-pass whole-genome sequencing and imputation offer significant cost savings, enabling substantial increases in sample size and statistical power. This approach is particularly promising in livestock breeding, providing an affordable means of screening individuals for deleterio...

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Bibliographic Details
Main Authors: David Wragg, Wengang Zhang, Sarah Peterson, Murthy Yerramilli, Richard Mellanby, Jeffrey J. Schoenebeck, Dylan N. Clements
Format: Article
Language:deu
Published: BMC 2024-01-01
Series:Genetics Selection Evolution
Online Access:https://doi.org/10.1186/s12711-024-00875-w