Translatome analysis reveals cellular network in DLK-dependent hippocampal glutamatergic neuron degeneration

The conserved MAP3K12/Dual Leucine Zipper Kinase (DLK) plays versatile roles in neuronal development, axon injury and stress responses, and neurodegeneration, depending on cell-type and cellular contexts. Emerging evidence implicates abnormal DLK signaling in several neurodegenerative diseases. Howe...

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Bibliographic Details
Main Authors: Erin M Ritchie, Dilan Acar, Siming Zhong, Qianyi Pu, Yunbo Li, Binhai Zheng, Yishi Jin
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2025-03-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/101173